The Best Ergonomic Mice of 2025: Tested & Reviewed

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Finding an ergonomic mouse that truly improves comfort and productivity without sacrificing performance can feel like a treasure hunt. After testing several popular options, we’ve identified the top picks for different needs and budgets. These mice prioritize wrist support and comfortable hand positioning to help prevent strain during long work or gaming sessions.

Our Top Picks

  1. Razer Basilisk V3 Pro (around $150): This mouse strikes a winning balance. Its ergonomic design, inspired by the popular Razer DeathAdder shape, cradles your palm comfortably while providing precise control for both work and gaming. We appreciate the customizable buttons, responsive scroll wheel, and lightweight construction that won’t weigh you down. While wireless, it still boasts excellent performance with 20,000 DPI sensitivity and a hyper-fast polling rate of 8,000 Hz.

  2. Logitech MX Master 3S (around $110): For those seeking ultimate productivity features, the Logitech MX Master 3S reigns supreme. Its sculpted design naturally positions your hand for comfort, while its magnetic charging system keeps it ready to go. This mouse offers a plethora of programmable buttons and gestures, including a thumb wheel for horizontal scrolling—a true time-saver when navigating spreadsheets or web pages.

  3. Logitech MX Anywhere 3 (around $100): This compact powerhouse is the perfect companion for laptop users who want ergonomic comfort on the go. Its lightweight design slips easily into bags, and its excellent Bluetooth connectivity ensures a reliable connection across devices. Don’t let the small size fool you; it packs Logitech’s signature wheel with adjustable scrolling modes (including hyperfast mode) and comfortable side grips for longer sessions.

Other Ergonomic Mice Worth Considering

While not quite making our top 3, these mice offer unique features or cater to specific preferences:

  • Razer Pro Click V2 ($120): A sleek, versatile choice that blends professional aesthetics with gaming performance. It boasts a comfortable curved shape, customizable RGB lighting, and robust tracking for both work and play.
  • Contour Design Rollermouse Red Wireless ($394): This unconventional device reimagines the mouse experience. Instead of clicking or scrolling with a ball beneath your fingers, this mouse uses a cylindrical trackball you operate with your thumb. It’s incredibly smooth and precise but comes at a hefty price and may take some time to adjust to.
  • Elecom Huge Trackball ($55): As the name suggests, this is a large trackball designed for full-hand usage, though its ergonomics are better suited for smaller hands. It’s sturdy with tactile buttons and a responsive ball, but its size can be overwhelming for some desks.

  • Keychron M6 ($70): If you like Logitech’s MX Master design but want something lighter and more gaming-focused, the Keychron M6 is a strong contender. Its dual-mode scroll wheel and horizontal scroll function make it versatile for productivity tasks, while its 4,000 Hz polling rate enhances responsiveness in games. However, quality control issues with some models can be a concern.

Remember that finding the perfect ergonomic mouse often involves personal preference. Consider your hand size, grip style, and primary use case when making your decision.